Contact +351 259 350 475

Paula Alexandra Martins de Oliveira Full Member

BIO

Name: Paula Alexandra Martins de Oliveira

Aggregation: Full Member

Orcid ID: 0000-0001-9519-4044

Email: pamo@utad.pt

URL:

Phone:

Research Tasks

Valorisation of bio-based products and and co-products

Resume

Publications

Anatomy and Imaging of Rat Prostate: Practical Monitoring in Experimental Cancer-Induced Protocols.
Ginja, Mário; Pires, Maria J.; Gonzalo-Orden, José; Seixas, Fernanda; Correia-Cardoso, Miguel; Ferreira, Rita; Fardilha, Margarida; Oliveira, Paula A.; Faustino-Rocha, Ana I. (2019) Anatomy and Imaging of Rat Prostate: Practical Monitoring in Experimental Cancer-Induced Protocols. DIAGNOSTICS 9 (3) :68. doi: 10.3390/diagnostics9030068. (Impact factor, Quartile: 2.489, Q2).
Dietary Supplementation with the Red Seaweed Porphyra umbilicalis Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice.
Santos, Susana; Ferreira, Tiago; Almeida, José; Pires, Maria J.; Colaço, Aura; Lemos, Sílvia; Gil da Costa, Rui M.; Medeiros, Rui; Bastos, Margarida M.; Neuparth, Maria J.; Abreu, Helena; Pereira, Rui; Pacheco, Mário; Gaivão; Rosa, Eduardo; Oliveira, Paula A.. (2019) Dietary Supplementation with the Red Seaweed Porphyra umbilicalis Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice. MARINE DRUGS 17 :615. doi: 10.3390/md17110615. (Impact factor, Quartile: 3.772, Q1).
Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice.
Santos, Joana M. O; Moreira-Pais, Alexandra; Neto, Tiago; da Silva, Sara P.; Oliveira, Paula A.; Ferreira, Rita; Mendes, Joaquim; Bastos, Margarida M.S.M; Lopes, Carlos; Casaca, Fátima; Silva, Sandra; Sweeney, Christopher; Medeiros, Rui; Gil da Costa, Rui M. (2019) Dimethylaminoparthenolide reduces the incidence of dysplasia and ameliorates a wasting syndrome in HPV16-transgenic mice. DRUG DEVELOPMENT RESEARCH 80 :824-830. doi: 10.1002/ddr.21565. (Impact factor, Quartile: 1.742, Q4).
Exercise training counteracts urothelia carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model.
Montero-Bullon, Javier-Fernando; Melo, Tânia; Ferreira, Rita; Padrão, Ana I.; Oliveira, Paula A.; Domingues, M. Rosário; Domingues, Pedro (2019) Exercise training counteracts urothelia carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model. SCIENTIFIC REPORTS 9 :13423. doi: 10.1038/s41598-019-49010-6. (Impact factor, Quartile: 4.011, Q1).
Exercise training counteracts urothelial carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model.
Montero-Bullon, Javier-Fernando; Melo, Tânia; Ferreira, Rita; Padrão, Ana Isabel; Oliveira, Paula A.; Domingues, M. R. M.; Domingues, Pedro (2019) Exercise training counteracts urothelial carcinoma-induced alterations in skeletal muscle mitochondria phospholipidome in an animal model. SCIENTIFIC REPORTS 9 :13423. doi: 10.1038/s41598-019-49010-6. (Impact factor, Quartile: 4.011, Q1).
Exercise Training Impacts Cardiac Mitochondrial Proteome Remodeling in Murine Urothelial Carcinoma.
Ferreira, Rita; Neuparth, Maria João; Nogueira-Ferreira, Rita; Magalhães, Sandra; Aroso, Miguel; Bovolini, José António; Lara Santos, Lúcio; Oliveira, Paula; Vitorino, Rui; Moreira-Gonçalves, Daniel (2019) Exercise Training Impacts Cardiac Mitochondrial Proteome Remodeling in Murine Urothelial Carcinoma. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20 (1) :127. doi: 10.3390/ijms20010127. (Impact factor, Quartile: 4.183, Q1).
One year of exercise training promotes distinct adaptations in right and left ventricle of female Sprague-Dawley rats.
Nogueira-Ferreira, Rita; Ferreira, Rita; Padrão, Ana I.; Oliveira, Paula A.; Santos, Manuel; Kavazis, Andreas N.; Vitorino, Rui; Moreira-Gonçalves, Daniel (2019) One year of exercise training promotes distinct adaptations in right and left ventricle of female Sprague-Dawley rats. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY 75 :561-572. doi: 10.1007/s13105-019-00705-4. (Impact factor, Quartile: 2.523, Q1).
Re: A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/ progressor potential of dapagliflozin (LETTER).
Oliveira, Paula; Seixas, Fernanda (2019) Re: A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/ progressor potential of dapagliflozin (LETTER). REGULATORY TOXICOLOGY AND PHARMACOLOGY 106 :346. doi: 10.1016/j.yrtph.2019.05.010. (Impact factor, Quartile: 2.996, Q1).
Studying humane endpoints in a rat model of mammary carcinogenesis.
Faustino-Rocha, Ana I.; Ginja, Mário; Ferreira, Rita; Oliveira, Paula A. (2019) Studying humane endpoints in a rat model of mammary carcinogenesis. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES 22 (6) :643-649. doi: 10.22038/ijbms.2019.33331.7957. (Impact factor, Quartile: 1.854, Q3).
The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: E cacy and Safety Observations
Ferreira, Tiago; Campos, Sandra; Silva, Mónica G.; Ribeiro, Rita; Santos, Susana; Almeida, José; Pires, Maria J.; Gil da Costa, Rui M.; Córdova, Cláudia; Nogueira, António; Neuparth, Maria J.; Medeiros, Rui; Bastos, Margarida M. S.M.; Gaivão, Isabel; Peixoto, Francisco; Oliveira, Maria M.; Oliveira, Paula A. (2019) The Cyclooxigenase-2 Inhibitor Parecoxib Prevents Epidermal Dysplasia in HPV16-Transgenic Mice: E cacy and Safety Observations INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20 :3902. doi: 10.3390/ijms20163902. (Impact factor, Quartile: 4.183, Q2).
Assessment of the exposure to heavy metals and arsenic in captive and freeliving black kites (Milvus migrans) nesting in Portugal.
Carneiro, M.; Oliveira, P.A.; Brandão, R.; Soeiro, V.; Pires, M.J.; Lavin, S.; Colaço, B. (2018) Assessment of the exposure to heavy metals and arsenic in captive and freeliving black kites (Milvus migrans) nesting in Portugal. Ecotoxicology And Environmental Safety 160 :191-196. doi: 10.1016/j.ecoenv.2018.05.040. (Impact factor, Quartile: 3.974, Q1).
Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice.
Moutinho, M.; Aragão, S.; Carmo, D.; Casaca, F.; Silva, S.; Ribeiro, J.; Sousa, H.; Pires, I.; Queiroga, F.; Colaço, B.; Medeiros, R.; Oliveira, P.A.; Lopes, C.; Bastos, M.; Gil da Costa, R. (2018) Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice. Anticancer Research 38 :1461-1466. doi: 10.21873/anticanres.12371. (Impact factor, Quartile: 1.865, Q4).
Exercise training protects against cancer-induced cardiac remodeling in an animal model of urothelial carcinoma.
Padrao, Ana Isabel; Nogueira-Ferreira, Rita; Vitorino, Rui; Carvalho, Dulce; Correia, Catarina; Neuparth, Maria Joao; Pires, Maria Joao; Faustino-Rocha, Ana Isabel; Santos, Lucio Lara; Oliveira, Paula Alexandra; Duarte, Jose Alberto; Moreira-Goncalves, Daniel; Ferreira, Rita (2018) Exercise training protects against cancer-induced cardiac remodeling in an animal model of urothelial carcinoma. Archives Of Biochemistry And Biophysics 645 :43435. doi: 10.1016/j.abb.2018.03.013. (Impact factor, Quartile: 3.118, Q2).
Exercise Training-induced Modulation in Microenvironment of Rat Mammary Neoplasms.
Figueira, A.C.C.; Figueira, M.C.; Silva, C.; Padrão, A.; Oliveira, P.A.; Ferreira, R.P.; Duarte, J.A. (2018) Exercise Training-induced Modulation in Microenvironment of Rat Mammary Neoplasms. INTERNATIONAL JOURNAL OF SPORTS MEDICINE 39 (12) :885-892. doi: 10.1055/a-0660-0198. (Impact factor, Quartile: 2.453, Q2).
Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice.
Araujo, Rita; Santos, Joana M. O.; Fernandes, Mara; Dias, Francisca; Sousa, Hugo; Ribeiro, Joana; Bastos, Margarida M. S. M.; Oliveira, Paula A.; Carmo, Diogo; Casaca, Fatima; Silva, Sandra; Medeiros, Rui; Gil da Costa, Rui M. (2018) Expression profile of microRNA-146a along HPV-induced multistep carcinogenesis: a study in HPV16 transgenic mice. Journal Of Cancer Research And Clinical Oncology 144 (2) :241:248. doi: 10.1007/s00432-017-2549-5. (Impact factor, Quartile: 3.282, Q2).
Intense Pulsed Light: Friend or Foe? Molecular Evidence to Clarify Doubts.
Ferreira, Liliana; Vitorino, Rui; Neuparth, Maria Joao; Rodrigues, David; Gama, Adelina; Faustino-Rocha, Ana I.; Ferreira, Rita; Oliveira, Paula A (2018) Intense Pulsed Light: Friend or Foe? Molecular Evidence to Clarify Doubts. Anticancer Research 38 (2) :779-786. doi: 10.21873/anticanres.12284. (Impact factor, Quartile: 1.865, Q4).
Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice.
Medeiros-Fonseca, B; Mestre, VF; Colaço, B; Pires, MJ; Martins, T; Gil da Costa, RM; Neuparth, MJ; Medeiros, R; Moutinho, MSS; Dias, MI; Barros, L; Bastos, MMSM; Félix, L; Venâncio, C; Ferreira, ICFR; Antunes, LM; Oliveira, PA. (2018) Laurus nobilis (laurel) aqueous leaf extract's toxicological and anti-tumor activities in HPV16-transgenic mice. FOOD & FUNCTION 9 :4419-4428. doi: 10.1039/c8fo00783g. (Impact factor, Quartile: 3.289, Q1).
Modelling human prostate cancer: Rat models.
Nascimento-Goncalves, Elisabete; Faustino-Rocha, Ana I.; Seixas, Fernanda; Ginja, Mario; Colaço, Bruno; Ferreira, Rita; Fardilha, Margarida; Oliveira, Paula A. (2018) Modelling human prostate cancer: Rat models. Life Sciences 203 :210-224. doi: 10.1016/j.lfs.2018.04.014. (Impact factor, Quartile: 3.234, Q2).
Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis.
Peirone, C.; Mestre, V. F.; Medeiros-Fonseca, B.; Colaço, B.; Pires, M. J.; Martins, T.; Gil da Costa, R. M.; Neuparth, M. J.; Medeiros, R.; Bastos, M. M. S. M.; Marques-Magallanes, J. A.; Oliveira, P. A. (2018) Ozone therapy prevents the onset of dysplasia in HPV16-transgenic mice-A pre-clinical efficacy and safety analysis. Biomedicine & Pharmacotherapy 104 :275-279. doi: 10.1016/j.biopha.2018.05.018. (Impact factor, Quartile: 3.457, Q2).
Potential effects of sulforaphane to fight obesity.
Martins, Tânia; Colaço, Bruno; Venâncio, Carlos; Pires, Maria J.; Oliveira, Paula A.; Rosa, Eduardo; Antunes, Luis M. (2018) Potential effects of sulforaphane to fight obesity. Journal Of The Science Of Food And Agriculture 98 (8) :2837-2844. doi: 10.1002/jsfa.8898. (Impact factor, Quartile: 2.379, Q1).
A Contrast Enhanced Ultrasonographic Study About the Impact of Long term Exercise Training on Mammary Tumor Vascularization.
Faustino Rocha, AIF, Gama, A, Oliveira, PA, Vanderperren, K, Saunders, JH, Pires, MJ, Ferreira, R, Ginja, M (2017) A Contrast Enhanced Ultrasonographic Study About the Impact of Long term Exercise Training on Mammary Tumor Vascularization. Journal Of Ultrasound In Medicine 36 :2459-2466. ISSN: 0278-4297. doi: 10.1002/jum.14287. (Impact factor, Quartile: 1.547, Q3).
A spontaneous high-grade undifferentiated mammary carcinoma in a seven-week-old female rat.
Faustino-Rocha, AI, Gama, A, Oliveira, PA, Alvarado, A, Ferreira, R, Ginja, M (2017) A spontaneous high-grade undifferentiated mammary carcinoma in a seven-week-old female rat. Experimental And Toxicologic Pathology 69 :241-244. ISSN: 0940-2993. doi: 10.1016/j.etp.2017.01.006. (Impact factor, Quartile: 1.975, Q2).
Antihistamines as promising drugs in cancer therapy.
Faustino-Rocha, AI, Ferreira, R, Gama, A, Oliveira, PA, Ginja, M (2017) Antihistamines as promising drugs in cancer therapy. Life Sciences 172 :27-41. ISSN: 0024-3205. doi: 10.1016/j.lfs.2016.12.008. (Impact factor, Quartile: 2.963, Q2).
Effects of exercise training on breast cancer metastasis in a rat model.
Alvarado, A, da Costa, RMG, Faustino-Rocha, AI, Ferreira, R, Lopes, C, Oliveira, PA, Colaço, B (2017) Effects of exercise training on breast cancer metastasis in a rat model. International Journal Of Experimental Pathology 98 :40-46. ISSN: 0959-9673. doi: 10.1111/iep.12225. (Impact factor, Quartile: 1.78, Q3).
Effects of lifelong exercise training on mammary tumorigenesis induced by MNU in female Sprague-Dawley rats.
Faustino-Rocha, AI, Gama, A, Oliveira, PA, Alvarado, A, Neuparth, MJ, Ferreira, R, Ginja, M (2017) Effects of lifelong exercise training on mammary tumorigenesis induced by MNU in female Sprague-Dawley rats. Clinical And Experimental Medicine 17 :151-160. ISSN: 1591-8890. doi: 10.1007/s10238-016-0419-0. (Impact factor, Quartile: 2.919, Q2).
Experimental mammary carcinogenesis - Rat models.
Alvarado, A, Faustino-Rocha, AI, Colaço, B, Oliveira, PA (2017) Experimental mammary carcinogenesis - Rat models. Life Sciences 173 :116-134. ISSN: 0024-3205. doi: 10.1016/j.lfs.2017.02.004. (Impact factor, Quartile: 2.963, Q2).
HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition.
da Costa, RMG, Aragao, S, Moutinho, M, Alvarado, A, Carmo, D, Casaca, F, Silva, S, Ribeiro, J, Sousa, H, Ferreira, R, Nogueira-Ferreira, R, Pires, MJ, Colaço, B, Medeiros, R, Venancio, C, Oliveira, MM, Bastos, MMSM, Lopes, C, Oliveira, PA (2017) HPV16 induces a wasting syndrome in transgenic mice: Amelioration by dietary polyphenols via NF-kappa B inhibition. Life Sciences 169 :19-Nov. ISSN: 0024-3205. doi: 10.1016/j.lfs.2016.10.031. (Impact factor, Quartile: 2.963, Q2).
Mast Cells in Mammary Carcinogenesis: Host or Tumor Supporters?
Faustino-Rocha, AI, Gama, A, Neuparth, MJ, Oliveira, PA, Ferreira, R, Ginja, M (2017) Mast Cells in Mammary Carcinogenesis: Host or Tumor Supporters? Anticancer Research 37 :1013-1021. ISSN: 0250-7005. doi: 10.21873/anticanres.11411. (Impact factor, Quartile: 1.937, Q3).
Modulation of mammary tumor vascularization by mast cells: Ultrasonographic and histopathological approaches.
Faustino-Rocha, AI, Gama, A, Oliveira, PA, Katrien, VE, Saunders, JH, Pires, MJ, Ferreira, R, Ginja, M (2017) Modulation of mammary tumor vascularization by mast cells: Ultrasonographic and histopathological approaches. Life Sciences 176 :35-41. ISSN: 0024-3205. doi: 10.1016/j.lfs.2017.03.013. (Impact factor, Quartile: 2.963, Q2).
Prognostic factors in MNU and DMBA-induced mammary tumors in female rats.
Alvarado, A, Lopes, AC, Faustino-Rocha, AI, Cabrita, AMS, Ferreira, R, Oliveira, PA, Colaço, B (2017) Prognostic factors in MNU and DMBA-induced mammary tumors in female rats. Pathology Research And Practice 213 :441-446. ISSN: 0344-0338. doi: 10.1016/j.prp.2017.02.014. (Impact factor, Quartile: 1.543, Q3).
Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice.
Da Costa, RMG, Araujo, R, Santos, JMO, Fernandes, M, Neto, T, Sousa, H, Ribeiro, J, Bastos, MMSM, Oliveira, PA, Carmo, D, Casaca, F, Silva, S, Lopes, C, Medeiros, R (2017) Regulation of miRNA-146a and miRNA-150 Levels by Celecoxib in Premalignant Lesions of K14-HPV16 Mice. Anticancer Research 37 :2913-2918. ISSN: 0250-7005. doi: 10.21873/anticanres.11644. (Impact factor, Quartile: 1.937, Q3).

Projects

VALORIZEBYPRODUCTS: Preclinical efficacy of sulforaphane or Brassica whole extract: a strategy to fight obesity and valorize Brassica byproduct
Running

Coordinator  /  Eduardo Rosa
Start date  /  2018/06 Funding  /  FCT/FEDER

See project details →

RUNaway - Running away from prostate cancer: Walking through the molecular basis of physical activity
Concluded

Coordinator  /  Paula Oliveira
Start date  /  2016/07 Funding  /  FCT/FEDER

See project details →

SPLICETHER - Application of splicing approaches to exploit alternative therapies for Lysosomal Storage Diseases: in vitro and in vivo studies
Concluded

Coordinator  /  Sandra Alves UTAD/CITAB Coordinator  /  Paula Oliveira
Start date  /  2016/05 Funding  /  FCT/FEDER

See project details →

IBERPHENOL- Cooperative research network in the field of polyphenols and their industrial applications
Concluded

Coordinator  /  Julián Rivas Gonzal UTAD/CITAB Coordinator  /  Eduardo Rosa
Start date  /  2015/10 Funding  /  INTERREG - POCTEP (Spain - Portugal)

See project details →

O efeito cardioprotetor do exercício físico no cancro
Concluded

Coordinator  /  Rita Ferreira UTAD/CITAB Coordinator  /  Paula Oliveira
Start date  /  2014/01 Funding  /  FCT

See project details →